Canadian Critical Care Trials Group Selected Research

Duration of Therapy

1/2022	Clinical Reasoning Behind Antibiotic Use in PICUs: A Qualitative Study.
1/2022	Antimicrobial treatment duration for uncomplicated bloodstream infections in critically ill children: a multicentre observational study.
11/2020	Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE) randomised clinical trial: study protocol.
1/2020	A pilot randomized controlled trial of 7 versus 14 days of antibiotic treatment for bloodstream infection on non-intensive care versus intensive care wards.
2/2018	7 versus 14 days of antibiotic treatment for critically ill patients with bloodstream infection: a pilot randomized clinical trial.
2/2016	Duration of Antimicrobial Treatment for Bacteremia in Canadian Critically Ill Patients.
4/2015	Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE): study protocol for a pilot randomized controlled trial.

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Canadian Critical Care Trials Group Research Topics

Disease

58	Critical Illness (Critically Ill) 01/2022 - 12/2001
15	Infections 01/2022 - 08/2006
15	Hemorrhage 11/2020 - 12/2001
13	Sepsis (Septicemia) 01/2022 - 10/2007
13	Septic Shock (Toxic Shock Syndrome) 07/2018 - 10/2002
9	Ventilator-Associated Pneumonia 07/2017 - 12/2006
7	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2019 - 01/2006
7	Venous Thromboembolism 11/2014 - 12/2005
6	Acute Kidney Injury (Acute Renal Failure) 01/2020 - 10/2012
6	Thrombocytopenia (Thrombopenia) 12/2014 - 06/2010
6	Renal Insufficiency (Renal Failure) 06/2014 - 12/2005
5	Hypotension (Low Blood Pressure) 11/2020 - 12/2008
5	Bacteremia 11/2020 - 04/2015
5	Delirium 10/2019 - 11/2012
5	Respiratory Insufficiency (Respiratory Failure) 04/2015 - 12/2005
5	Thromboembolism 12/2014 - 12/2005
5	Multiple Organ Failure (MODS) 09/2011 - 12/2001
4	Ulcer 07/2017 - 01/2009
4	Wounds and Injuries (Trauma) 02/2015 - 10/2002
4	Venous Thrombosis (Deep-Vein Thrombosis) 12/2014 - 12/2005
4	Hypothermia 05/2010 - 01/2006
3	Shock 06/2017 - 10/2009
3	Heart Arrest (Cardiac Arrest) 06/2015 - 03/2009
3	Pulmonary Embolism 12/2014 - 01/2008
3	Thrombosis (Thrombus) 12/2014 - 05/2014
2	Bacterial Infections (Bacterial Infection) 01/2022 - 02/2018
2	Brain Injuries (Brain Injury) 01/2022 - 11/2020
2	Clostridium Infections 11/2020 - 04/2015
2	Hypercalcemia (Milk Alkali Syndrome) 01/2020 - 01/2017
2	Anemia 01/2019 - 01/2018
2	Coinfection 02/2018 - 04/2015
2	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 01/2018 - 12/2016
2	Pneumonia (Pneumonitis) 09/2017 - 11/2010
2	Vitamin D Deficiency 01/2017 - 09/2012
2	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 12/2015 - 01/2009
2	Death (Near-Death Experience) 07/2015 - 05/2012
2	Pain (Aches) 04/2015 - 04/2011
2	Human Influenza (Influenza) 04/2015 - 03/2010
2	Bronchiolitis 12/2005 - 10/2002
1	COVID-19 10/2021
1	Vasoplegia 11/2020
1	Hypersensitivity (Allergy) 11/2020
1	Hemolysis 01/2020
1	Hypoglycemia (Reactive Hypoglycemia) 01/2020
1	Inflammation (Inflammations) 01/2020
1	Congenital Heart Defects (Congenital Heart Defect) 01/2020
1	Mood Disorders (Mood Disorder) 01/2019
1	Dysbiosis 12/2018
1	Aneurysm (Aneurysms) 01/2018

Drug/Important Bio-Agent (IBA)

14	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 08/2004
10	Heparin (Liquaemin)FDA LinkGeneric 03/2015 - 06/2010
6	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 12/2014 - 12/2005
6	Hemoglobins (Hemoglobin)IBA 09/2011 - 09/2004
5	Hypnotics and Sedatives (Sedatives)IBA 01/2022 - 02/2006
5	AnticoagulantsIBA 01/2018 - 01/2008
4	Dalteparin (Dalteparin Sodium)FDA Link 12/2014 - 01/2008
4	Pharmaceutical PreparationsIBA 06/2014 - 12/2005
3	Vitamin D FDA LinkGeneric 01/2020 - 09/2012
3	Hydrocortisone (Cortisol)FDA LinkGeneric 07/2018 - 07/2010
3	Neuromuscular Blocking AgentsIBA 12/2017 - 02/2006
3	Lactic Acid (Lactate)FDA LinkGeneric 07/2017 - 10/2002
3	Adrenal Cortex Hormones (Corticosteroids)IBA 06/2017 - 02/2003
3	AlbuminsIBA 01/2016 - 06/2012
3	Crystalloid SolutionsIBA 01/2016 - 10/2007
3	AntioxidantsIBA 05/2015 - 08/2006
3	Glutamine (L-Glutamine)FDA Link 05/2015 - 08/2006
3	Oxygen (Dioxygen)IBA 04/2015 - 12/2005
3	CreatinineIBA 10/2013 - 01/2008
3	Saline SolutionIBA 10/2012 - 12/2008
2	Biomarkers (Surrogate Marker)IBA 11/2020 - 01/2020
2	boldenone undecylenate (Equipoise)IBA 11/2020 - 02/2018
2	ChloridesIBA 01/2018 - 07/2017
2	Pantoprazole (Protonix)FDA LinkGeneric 07/2017 - 01/2017
2	Opioid Analgesics (Opioids)IBA 10/2015 - 11/2012
2	Serotonin (5 Hydroxytryptamine)IBA 06/2014 - 06/2010
2	Starch (Cornstarch)IBA 10/2012 - 11/2010
2	CatecholaminesIBA 09/2012 - 07/2010
2	Analgesics (Analgesic Drugs)IBA 04/2011 - 02/2006
2	Colloids (Colloid)IBA 12/2008 - 10/2007
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 01/2020

Therapy/Procedure

22	Artificial Respiration (Mechanical Ventilation) 01/2021 - 12/2001
21	Critical Care (Surgical Intensive Care) 01/2020 - 09/2004
20	Therapeutics 01/2022 - 12/2005
9	Resuscitation 11/2020 - 01/2007
8	Length of Stay 11/2020 - 12/2001
8	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2020 - 10/2012
8	Erythrocyte Transfusion 01/2019 - 10/2002
7	Duration of Therapy 01/2022 - 04/2015
3	Early Ambulation 01/2019 - 07/2016
2	Extracorporeal Membrane Oxygenation 11/2020 - 03/2009
2	Positive-Pressure Respiration (Positive End-Expiratory Pressure) 12/2017 - 12/2005
2	Device Removal (Removal, Device) 04/2015 - 11/2012
2	Mechanical Ventilators (Ventilator) 04/2015 - 11/2013
2	Enteral Nutrition (Feeding, Tube) 12/2013 - 12/2012
1	Personal Protective Equipment 10/2021
1	Ventilator Weaning 01/2021
1	Cardiopulmonary Bypass (Heart-Lung Bypass) 01/2020
1	Analgesia 10/2019
1	Vascular Access Devices (Arterial Line) 02/2018
1	Immunotherapy 01/2018